Liebe Kollegen, am kommenden Donnerstag den **23.6. um 14 ct (Raum 6.020)** wird es wieder einen Vortrag im Rahmen des AG-Griebel Oberseminars geben. A.V. Kuznetsov: Microfluidics of left-right symmetry breaking in mammal embryos. (Dept. of Mechanical & Aerospace Engineering, North Carolina State University) Abstract siehe unten. Hierzu sind alle Interessierten herzlich eingeladen. Viele Gruesse Markus Burkow Dear colleagues, it is our pleasure to announce the following talks in the seminar of AG-Griebel for Thursday, 23th Jun, 2pm Room 6.020: A.V. Kuznetsov: Microfluidics of left-right symmetry breaking in mammal embryos. (Dept. of Mechanical & Aerospace Engineering, North Carolina State University) Abstract below. Best regards, Markus Burkow Abstract: We developed an approximate method for modelling the flow of embryonic fluid in a ventral node. We simplified the problem as flow in a 2D cavity; the effect of rotating cilia was modeled by specifying a constant vorticity at the edge of the ciliated layer. We also developed an approximate solution for morphogen transport in the nodal pit. The solutions were obtained utilizing the proper generalized decomposition (PGD) method. We compared our approximate solutions with the results of numerical simulation of flow caused by the rotation of 81 cilia, and obtained reasonable agreement in most of the flow domain. We discuss locations where agreement is less accurate. The obtained semi-analytical solutions simplify the analysis of flow and morphogen distribution in a nodal pit. -- Markus Burkow Institut für Numerische Simulation Rheinische Friedrich-Wilhelms Universität Bonn Wegelerstrasse 4 , Room 0.015 D-53115 Bonn Germany Tel : +49 228 73 60471 URL : http://wissrech.ins.uni-bonn.de/people/burkow.html Mail: burkow@ins.uni-bonn.de